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Dr Khaled Assi
Lecturer in Pharmaceutical and Biomedical Analysis
  • Telephone: +44 (0) 1274 234703
  • Email: k.h.a.assi@bradford.ac.uk

Dr. Assi has research experience in the development of pharmaceutical and bioanalytical assay methods. This includes the optimisation and validation of bioanalytical techniques for qualitative and quantitative determination of inhaled drugs and its metabolites in aqueous and biological fluids for bioequivalence and pharmacokinetic studies. He also has experience in assessing the in-vitro quality of the dose emitted from inhalation systems (dry powder inhalers [DPIs], metered dose inhalers [MDIs] and nebulisers) and in the determination of the resistance characteristics and comparative product features of various marketed DPIs to identify the optimum inhalation flow rate and appropriate DPI for different patients.

Recent Publications:

1.D.K. Nadarassan, H Chrystyn, BJ Clark, KH Assi “Validation of a high-performance liquid chromatography assay for quantitation of formoterol in urine samples after inhalation using UV detection”, Journal of Chromatography B ( Accepted for publication)

2.K.H. Assi, W. Tarsin, and H.Chrystyn, “High performance liquid chromatography assay method for simultaneous quantitation of formoterol and budesonide in Symbicort Turbuhaler”, J. Pharm. Biomed. Analysis. 41 (2006) 325-328.

3.WY Tarsin, KH Assi, SB Pearson, H Chrystyn, “Emitted dose estimates from Seretide® Diskus® and Symbicort®Turbuhaler® following inhalation by severe asthmatics”, International Journal of Pharmaceutics 316 (2006) 131–137

4.Al-Amoud AI;Clark BJ;Assi KA;Chrystyn H “Determination of the bioavailability of gentamicin to the lungs following inhalation from two jet nebulizers” Br J Clin Pharmacol, 59 (5) (2005), 542-545.

5.W. Tarsin, K.H. Assi and H.Chrystyn “In-Vitro inhalation flow rate dependent dosage emission and inconsistency from a combination of budesonide and efometrol in a dry powder inhaler” J Aersol Med 2004; 17(1): 25-32