The Institute of Pharmaceutical Innovation

Monday 10th December, 2007 Major advance in crystal structure prediction

Dr. Marcus Neumann of Avant-garde Materials Simulation (AMS) in Paris has achieved a major advance in the prediction of the crystal structures of small organic molecules as part of an international scientific event.

He collaborated with researchers Drs. Frank Leusen and John Kendrick from the Institute of Pharmaceutical Innovation (IPI) at the University of Bradford, who applied AMS technology in the Blind Test in Crystal Structure Prediction, organised by the University of Cambridge and hosted by the Cambridge Crystallographic Data Centre (CCDC).

The three researchers have met the challenge by correctly predicting the crystal structures of all four Blind Test compounds using computational methods without any experimental input.

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Monday 3rd December, 2007 Professor Rob Forbes academic partner in £1M+ Project

UK Consortium Led By Paraytec Ltd In £1M+ Project To Develop Novel Analytical Instrumentation To Detect Aggregation In Biopharmaceutical Processing.

A multi-disciplinary UK consortium of partners including Avecia, Intertek ASG, Lonza, Paraytec and the IPI (University of Bradford) has recently been awarded research grants by the Technology Strategy Board and the Engineering and Physical Sciences Research Council. The part funded £1M+ project is to develop novel analytical instrumentation to detect aggregation in biopharmaceutical processing. Aggregation or the ‘sticking together’ of molecules is a major problem in medicine. At best it can reduce the effectiveness of a drug and at worst it can have detrimental health effects.

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